• Supplements are considered foods.
  • No specific dosage is recommended.
  • Clinical trials have used doses up to a gram or more.
  • Safety has been established at doses of two grams or higher per day.
  • There is a dose-dependent increase in NAD metabolism.
  • NAD levels can be increased by avoiding metabolic stresses.
  • Metabolic stresses that disturb the NAD system include DNA damage from the sun, alcohol metabolism, inflammation, and oxidative stress.
  • NR helps maintain the NAD system.

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