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Estrogen's Impact on Learning and Memory in Perimenopause
The decline in estrogen levels during perimenopause affects the production of neurotransmitters like acetylcholine and glutamate, crucial for encoding and developing new memories. Reduced estrogen results in a decrease in these neurotransmitters, making it challenging to encode new information effectively. This memory issue is not about forgetting but about difficulties in encoding information initially, similar to ADHD but with a distinct mechanism.