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Addressing the Gut-Skin Axis: A Root Cause Approach to Chronic Skin Conditions
Dr. Kara Fitzgerald | New Frontiers in Functional Medicine, Longevity, Epigenetics
Mucus Matters: Balance and Protection in Skin Health
Certain bacteria play a crucial role in skin health by consuming old mucus and signaling goblet cells to produce more mucus, essential for protecting the body's one-cell-thick lining. In patients with eczema, a pattern of low commensal bacteria and inflammatory overgrowth is often observed, with histamine-producing bacteria like Citrobacter and Klebsiella being significant contributors to symptoms. These bacteria may exacerbate eczema symptoms, particularly the itch-scratch cycle. Digestive markers often show abnormalities, including low levels of secretory IgA, while high anti-gladon levels correlate with increased secretory IgA. Elevated Calprotectin may also indicate inflammation in the colon. Understanding these interactions offers insight into managing eczema and highlights the uniqueness of each patient's condition.
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