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#069 COVID Vaccine Myths, Questions, and Rumors with Rhonda Patrick and Roger Seheult
FoundMyFitness
Importance of Locking Viral Proteins in Prefusion Confirmation for Vaccines
Locking viral proteins in prefusion confirmation is a crucial step for vaccines, as it triggers a confirmational change in the virus. This is significant because vaccines such as Moderna, Pfizer-BioNTech, Johnson & Johnson, and Novavax contain a special insertion to lock the spike protein, thanks to the work of structural biologists like Dr. Jason McClellan. This innovation was originally developed for respiratory syncytial virus (RSV) and has been instrumental in vaccine development.
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