AI-powered
podcast player
Listen to all your favourite podcasts with AI-powered features
1min snip
Video Episode | Mr. Happy | The Next Generation - Part 2
In Search of Insight
Imbalance Breeds Dependence
Activation of the endogenous opioid biosynthesis pathway occurs through the interaction of dopamine and DOPAL. Disruptions to aldehyde dehydrogenase activity can lead to the accumulation of DOPAL, diverting metabolic processes towards morphine production. Factors like low levels of NAD or essential minerals can inhibit this enzyme, resulting in chronic morphine production akin to prolonged narcotic use. This chronic production causes downregulation of receptors and pathways, leading to long-term homeostatic imbalances that persist even after the initial disruption is resolved, necessitating a recovery period for the system to reset.
00:00
Transcript
Episode notes
Get the Snipd
podcast app
Unlock the knowledge in podcasts with the podcast player of the future.
AI-powered
Discover
highlights
Listen to the best highlights from the podcasts you love and dive into the full episode
Save any
moment
Hear something you like? Tap your headphones to save it with AI-generated key takeaways
Share
& Export
Send highlights to Twitter, WhatsApp or export them to Notion, Readwise & more
AI-powered
podcast player
Listen to all your favourite podcasts with AI-powered features
Discover
highlights
Listen to the best highlights from the podcasts you love and dive into the full episode