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#249 – Albert Bourla: Pfizer CEO
Lex Fridman Podcast
What are Phases 1 - 3 in Vaccine Studies?
Vaccine studies progress through multiple phases to identify the right vaccine, dose, and schedule. Phase 1 involves testing smaller doses in humans, monitoring for reactogenicity, and measuring immune responses. Different vaccines and doses are tested in various age groups. Phase 2 involves further testing of the selected vaccines and doses. Phase 3 is a large study involving thousands of people to test the selected vaccine against a placebo. The study is blinded to ensure the right vaccine is used, and participants are monitored for disease incidence and safety profile differences between vaccinated and non-vaccinated individuals.
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