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#135 Guideline Directed Medical Therapy Part II: 5 Pearls Segment

Core IM | Internal Medicine Podcast

NOTE

Diversity in Health Outcomes: Don't Overlook the Evidence

The analysis reveals a significant mortality benefit of Isodilin hydralazine when added to existing guideline-directed medical therapy (GDMT) in a study focused on the African American population. This highlights the importance of not dismissing these results, as they suggest efficacy in this subgroup. However, the absence of data regarding the effectiveness of hydral Isosorbide and Dinitrate in other racial groups raises questions about broader applicability. The lack of evidence does not support the notion that these drugs are ineffective across different races. Additionally, considerations regarding the etiology of cardiomyopathy may serve as potential confounders, suggesting that further research is needed to fully understand the impact of these therapies across diverse populations.

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