Observational study with 160,000 participants showed that individuals with high inflammation, indicated by high C-reactive protein and low serum albumin levels, had a 171% increase in the risk of all-cause mortality. Additionally, they had a 316% increase in cancer mortality, 233% increase in cardiovascular mortality, and 217% increase in cerebrovascular mortality. Although inflammation may not directly cause these mortalities, the significant findings in epidemiology suggest a causal relationship between inflammation and disease.

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