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Simple ways to improve gut health | Dr. Karan Rajan

ZOE Science & Nutrition

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The Interconnection of Microbiome Development and Immune Function in Early Life

The development of the microbiome in early childhood plays a critical role in the functioning of the immune system, establishing a complex interplay between the two. Research indicates that this relationship is particularly pivotal within the first few years of life, as children cultivate their microbiome. Initially, a fetus is considered sterile, and the colonization of its microbiome begins at birth, which is influenced by the mode of delivery—with vaginal births transmitting distinct microbes through the birth canal, while cesarean sections expose infants to different microbial sources, such as maternal skin. Following birth, factors such as breastfeeding, environmental exposure, and family dynamics further shape the microbiome. Breastfed infants benefit from unique bacteria present in breast milk, while formula-fed infants may have different microbial characteristics. Additionally, living conditions, urban versus rural environments, and interactions with pets or siblings can significantly impact microbiome development. This nuanced understanding highlights the importance of nurturing the microbiome during early childhood to support immune health and overall well-being.

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