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Peter Attia, MD On Becoming a Centenarian Decathlete, Metabolic Health & All Things Zone 2

The Rich Roll Podcast

NOTE

Lack of sleep and increase in diabetes chance

Experimental data supports the link between lack of sleep and an increased chance of diabetes. A glycemic clamp experiment was conducted to measure glucose disposal and insulin sensitivity. The test involved giving participants insulin and glucose to maintain a normal glycemic response. By measuring the amount of insulin required, the experiment accurately determined an individual's insulin sensitivity. Participants in the study underwent two weeks of sleep deprivation, receiving only four hours of sleep per night. After this period, glucose disposal decreased by 50%, indicating a significant reduction in insulin sensitivity. These findings highlight the detrimental effects of sleep deprivation on the body's ability to regulate glucose levels and raise the risk of developing diabetes.

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