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The Peter Attia Drive cover image

#235 ‒ Training principles for mass and strength, changing views on nutrition, creatine supplementation, and more | Layne Norton, Ph.D.

The Peter Attia Drive

NOTE

The Role of Testosterone in Muscle Mass Growth

Testosterone can increase satellite cell numbers in muscles, which can increase muscle mass potential./nSatellite cells are cells that sit on the outside of muscle fibers and can be donated to the muscle through resistance training or testosterone./nThe myonuclear domain theory suggests that muscle fibers can only grow as big as the number of myonuclei they have./nMen tend to have more lean mass than women due to hormonal differences, particularly during puberty./nExogenous levels of testosterone can further increase the number of myonuclei and help reach a higher ceiling for muscle growth.

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