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#304 – NEW: Introducing quarterly podcast summaries - Peter shares his biggest takeaways on muscle protein synthesis, VO2 max, toe strength, gut health, and more

The Peter Attia Drive

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Muscle Protein Synthesis and Amino Acid Turnover in Muscle and the Brain

The activation of M-tore signals muscle protein synthesis, especially when combined with protein intake and exercise. Around 300 grams of amino acids are utilized daily, with the majority being recycled endogenous amino acids. The turnover of muscle takes between 50 and 100 days, meaning every muscle in the body is completely renewed every two to three months. In contrast, the turnover of brain proteins occurs more rapidly within about 30 days, implying that the amino acids in the brain are constantly being replaced.

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