Regenerative Health with Max Gulhane, MD cover image

76. Key Role of Vitamin D & Sunlight in Health | Michael Holick, MD, PhD

Regenerative Health with Max Gulhane, MD

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Vitamin D: The Framework of Bone Strength

Vitamin D plays a crucial role in activating calcium and phosphate absorption in the intestines, essential for building and maintaining the structural integrity of bones. Upon activation in the liver and kidneys, the active form of vitamin D aids in forming a strong collagen matrix, allowing calcium and phosphate to crystallize effectively, much like mixing concrete for strength. When vitamin D levels are deficient, the body prioritizes maintaining blood calcium levels, which leads to increased parathyroid hormone production. This hormone prompts osteoclasts to break down bone tissue, releasing calcium into circulation to safeguard blood calcium levels, ultimately compromising bone health.

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