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Memory and Forgetting

Radiolab

ANECDOTE

Memory Manipulation in Rats

  • Researchers used mild electric shocks and tones to study memory formation in rats.
  • When a tone precedes a shock, rats learn to associate the two and freeze in anticipation.
  • Injecting a protein-synthesis-inhibiting chemical during memory formation prevents the memory from consolidating.
  • This suggests that memories require active protein synthesis to solidify.
  • The rats, unable to form the memory, exhibit perpetual surprise upon repeated shocks.
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