Utilizing nutrition strategically can significantly impact disease management, particularly through meticulous control of macronutrient intake, including fats, proteins, and carbohydrates, to regulate glucose availability. Specific compounds like sodium phenylbutyrate, oxaloacetate, and EGCG offer varying benefits, but the most potent agent is the six diazo, five-oxo l-norlucyne (D-O-N), which effectively lowers glutamine levels and is integral to a therapeutic approach known as pulse therapy. This method emphasizes the importance of consistent glucose control, ideally maintaining glucose levels between 55 to 65 mg/dL daily, with specific timing for the administration of D-O-N before interventions like hyperbaric therapy, highlighting the significance of dosing and scheduling in treatment efficacy.

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