The introduction of novel entities such as nuclear waste, microplastics, and endocrine disruptors into the biosphere poses significant threats to life on Earth, as these compounds accumulate and disrupt ecosystems. Additionally, aerosol loading, often resulting from urban pollution, alters the Earth's energy balance by reflecting solar radiation, which changes monsoon systems and paradoxically cools the planet. This environmental dilemma is compounded by serious human health implications, yet human health considerations are not used in defining planetary boundaries, highlighting a critical oversight in environmental management.

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