Different Forms of Neuroplasticity: Long-Term Potentiation

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Neuroplasticity encompasses various types, including long-term potentiation (LTP), which involves strengthening connections between neurons due to repeated firing closely together in time. Contrary to popular belief, the phrase 'fire together, wire together' was not coined by Donald Hebb but by Carla Schatz, referring to LTP and other forms of neuroplasticity in developmental stages. LTP occurs when a small group of neurons are active closely together in time, leading to strengthened connections, facilitating easier communication between neurons through electrical and chemical activity.

In this episode, I discuss working memory, which is critical for learning and productivity, strategy setting, goal seeking, and navigating new environments. I explain the key role of dopamine and the biological mechanisms underlying working memory and how working memory differs from both short- and long-term memory.

I also describe science-supported tools to enhance working memory and attention—including zero- or low-cost behavioral, supplemental and pharmacologic approaches. I include how to assess your working memory and how to use memory tasks to determine your baseline dopamine levels in certain brain circuits.

This episode provides listeners with highly actionable tools to assess and improve their attention to specific tasks and task-switching capacity and to enhance their overall productivity.

For show notes, including referenced articles and additional resources, please visit hubermanlab.com.