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#204 NephMadness 2020: SGLT2 Inhibitors
The Curbsiders Internal Medicine Podcast
The Role of SGLT2 Inhibitors in Cardiovascular Outcomes
In an episode before episode 100s, the ACP released diabetes guidelines recommending an A1C between 7 and 8%. Previous trials with older agents didn't prevent cardiovascular and renal issues. However, SGLT2 inhibitors showed significant improvements in hard endpoints in a short amount of time. The Kaplan-Meyer curve quickly separates after taking these pills, improving mortality almost immediately.
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