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#1077 - Johann Hari

The Joe Rogan Experience

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Exploring the Controversy of Chemical Imbalance and Antidepressants

The controversy around the concept of chemical imbalance in the brain and the effectiveness of antidepressants is a complex issue. While most scientists agree that low serotonin correlates with depression, it is not seen as the sole cause. The idea that depression causes serotonin imbalance is discredited, and the concept of chemical imbalance has been suggested to benefit drug companies. Antidepressants have an average impact of moving people 1.8 points on the Hamilton scale, indicating they provide some relief but do not solve the underlying issue for most individuals.

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