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Discussing Ultra Processed Foods and Weight Loss Drugs with Stephan Guyenet

Metagenics Institute Podcast

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The differential impact of food-induced GLP1 and drug-induced GLP1 on the body

Studies on rodents suggest that while food-induced GLP1 mostly acts in the periphery and has a short-lived effect, drug-induced GLP1 elevates GLP1 levels all day, reaching the brain and activating GLP1 receptors. This differential impact on the body implies that drug-induced GLP1 is not equivalent to food-induced GLP1 and can lead to reduced overall caloric intake.

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