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David Reich - How One Small Tribe Conquered the World 70,000 Years Ago

Dwarkesh Podcast

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Epigenetic gene regulation by Methylated CG pairs

The process of collecting and analyzing epigenetic modification data reveals unexpected findings that challenge assumptions about genetic functions. Epigenetic modifications, such as methylation, play a crucial role in regulating gene activity, influenced by cellular environments and varying across different cells and species. These modifications are not encoded in the DNA sequence itself but can be inherited, suggesting a complex layer of biological regulation. This insight encourages exploring less-studied areas of genetics, hinting at the potential for more surprises in understanding biological processes.

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