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** Stress & Hormesis**
Hormesis is the concept of sublethal exposure to stress or toxins, which at high levels can be lethal, but at low to moderate levels induces stress resistance. There are over 600 known hormetic stressors including exercises, cold exposure, heat exposure, UV radiation, and nutritional stressors like polyphenols. Exposure to small doses of intermittent stress upregulates protective genes, leading to increased stress fitness and resilience at the cellular level.