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Economist Podcasts cover image

Lost in stagnation? Japan’s economic paradox

Economist Podcasts

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Biological Differences in Drug Testing

The challenge in testing how drugs work on women stems from biological differences between mice and humans such as the absence of periods in mice and distinct hormone cycles. Additionally, many mouse trials utilize young males with untested immune systems, contributing to the difficulty in predicting drug reactions accurately.

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Speaker 2
Recently, we had a segment on the intelligence about why it was so hard
Speaker 4
to test how drugs would work on women. Because mice, for example, most mice don't have periods. The hormone cycles are very different. I'm interested in whether that's any of the reason for this very small percentage.
Speaker 2
That is part of the reason. Yes, there are those biological differences between mice and humans. And many mouse trials use young males with untested immune systems. Human

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