AI-powered
podcast player
Listen to all your favourite podcasts with AI-powered features
The Gut as an Endocrine Organ and Its Role in Metabolism
The gut is an endocrine organ, secreting hormones and neuropeptides that affect metabolism. Inflammation in the gut leads to hormonal imbalance and various health problems. The gut-brain connection is well-known, but it is not solely about inflammation or leaky gut. Trauma and abuse can also contribute to metabolic disorders. Psychological and social stressors are linked to both mental illness and metabolic disorders. Individuals who experienced childhood abuse and adversity are more likely to have mental disorders such as depression, personality disorders, anxiety disorders, addiction, and suicidality. They are also at a higher risk of developing obesity, diabetes, and cardiovascular disease, which can result in premature death.