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The Art of Manliness cover image

The Safe, Effective Supplement That Can Improve Your Body and Brain

The Art of Manliness

NOTE

Elevated Creatinine: A Sign of Supplementation, Not Sickness

Elevated creatinine levels often occur with creatine supplementation, but this increase does not indicate impaired kidney function. Instead, higher creatinine levels result from the metabolism of creatine, which is a common physiological response. Even though healthcare providers use creatinine as a marker to evaluate kidney health, elevated levels in individuals taking creatine are typically false positives. It's essential for those on creatine supplementation to inform their healthcare providers, particularly nephrologists, to avoid misinterpretations of kidney function tests. Strenuous exercise and high dietary protein intake also contribute to elevated creatinine, indicating that multiple factors can influence test results. For accurate kidney function assessment, patients can request additional tests such as cystatin C, which may provide a clearer picture of kidney health without the confounding effects of creatinine. Overall, creatine is considered safe for healthy individuals, though those with existing kidney conditions should consult with healthcare professionals before starting supplementation.

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