Class agnostic annotation enables broad applicability of segmentation models without the need for explicit class labels. By treating any boundary in images as an object, the model can recognize a variety of small, unnamed objects, including those found in specialized domains like medicine. A large dataset annotated in this manner allows the model to perform out of the box for untrained applications. However, certain domains may require additional expertise or fine tuning to accurately segment objects. Various adaptations of the model, like CellSAM, enhance domain-specific performance through either fine tuning with extra data or prompt-based guidance that leverages the model's existing knowledge. Both approaches are vital to ensure the model correctly identifies and segments the objects of interest, emphasizing the importance of clear indications in production scenarios.

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