Exploring Clotho: The Compound That Could Change Alzheimer’s Risk

This time, we have a very special episode I recorded with my close friend Kevin Rose in person at his house. We trade our latest discoveries, and I think it’s one of our best. Tons of actionable takeaways and laughing fits. We cover dozens of topics: new projects, what I’ve done on my recent sabbatical after the podcast’s 10th anniversary, Kevin’s latest findings and shenanigans, real vampire protocols, and much, much more.

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Timestamps:

[00:00] Start

[07:40] A sabbatical recap and future podcasting plans.

[15:25] PicStudio's disturbingly realistic AI-generated portraits.

[17:25] Kevin's new Jess Mascetti tattoo.

[18:08] Vampire facials and a platelet-rich plasma (PRP) problem.

[22:22] Tequila martinis.

[24:20] Romance versus radical planning.

[32:50] Bobby Fingers.

[34:46] Training for the hunt.

[41:15] Fairbanks fun.

[42:11] European dating.

[43:46] Hasty oral hygiene with Feno.

[48:00] The mysteries of mimetic contagion.

[49:21] Big book beginnings.

[50:15] Kevin's AI-powered investment advisor experiment.

[51:34] Publishing strategies.

[52:25] Why you should visit Ryan Holiday's bookstore.

[53:53] A visit from a 14-year-old Toaster.

[54:40] The Dog Aging Project.

[55:14] Original Love: Zen master Henry Shukman's new app.

[55:37] Kevin's Zen Hell week.

[58:10] Dena Dubal's Alzheimer's treatment breakthrough.

[1:07:45] Small expectations for a medium turn large.

[1:14:44] Inexplicable skill efficacy and hypernatural happenings.

[1:23:47] Another outstanding Addison-refined refreshment.

[1:24:39] Unmissable media recommendations.

[1:31:18] Taking ketamine seriously.

[1:39:37] More tequila and tattoo talk.

[1:40:27] What's the Flux?

[1:45:34] A children's book for adults.

[1:46:40] Are you hunting antelope or field mice?

[1:48:12] Analyzing what "chill" looks like for me.

[1:57:02] Parting thoughts.

*

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Past guests on The Tim Ferriss Show include Jerry Seinfeld, Hugh Jackman, Dr. Jane Goodall, LeBron James, Kevin Hart, Doris Kearns Goodwin, Jamie Foxx, Matthew McConaughey, Esther Perel, Elizabeth Gilbert, Terry Crews, Sia, Yuval Noah Harari, Malcolm Gladwell, Madeleine Albright, Cheryl Strayed, Jim Collins, Mary Karr, Maria Popova, Sam Harris, Michael Phelps, Bob Iger, Edward Norton, Arnold Schwarzenegger, Neil Strauss, Ken Burns, Maria Sharapova, Marc Andreessen, Neil Gaiman, Neil de Grasse Tyson, Jocko Willink, Daniel Ek, Kelly Slater, Dr. Peter Attia, Seth Godin, Howard Marks, Dr. Brené Brown, Eric Schmidt, Michael Lewis, Joe Gebbia, Michael Pollan, Dr. Jordan Peterson, Vince Vaughn, Brian Koppelman, Ramit Sethi, Dax Shepard, Tony Robbins, Jim Dethmer, Dan Harris, Ray Dalio, Naval Ravikant, Vitalik Buterin, Elizabeth Lesser, Amanda Palmer, Katie Haun, Sir Richard Branson, Chuck Palahniuk, Arianna Huffington, Reid Hoffman, Bill Burr, Whitney Cummings, Rick Rubin, Dr. Vivek Murthy, Darren Aronofsky, Margaret Atwood, Mark Zuckerberg, Peter Thiel, Dr. Gabor Maté, Anne Lamott, Sarah Silverman, Dr. Andrew Huberman, and many more.

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