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Anna Lembke, MD on The Neuroscience of Addiction, Dopamine Fasting & The Opioid Crisis

The Rich Roll Podcast

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Neuroscientific Explanation of Brain's Balance and Homeostasis

The brain operates like a teeter-totter, balancing pleasure and pain. It seeks to maintain a level balance, known as homeostasis. Pleasurable experiences tip the balance towards pleasure, releasing dopamine, but the brain quickly adapts by regulating dopamine receptors to restore homeostasis. This causes 'gremlins' to hop on the pain side of the balance until the scale tips towards pain, resulting in the opponent process reaction. This explains the craving for more pleasure-inducing experiences. Waiting allows the 'gremlins' to hop off and restore balance.

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