The Science of Psychotherapy cover image

In Conversation with Lou Cozolino

The Science of Psychotherapy

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Understanding the Salience Network: Appraisal and Response

The amygdala plays a crucial role in the salience network, which is essential for evaluating stimuli as significant or not. It acts as an organ of appraisal, assessing experiences as good or bad, guiding approach or avoidance actions. This network has evolved from the primitive functions of the amygdala, influencing both emotional responses and autonomic nervous system activation, highlighting the interconnectedness of different brain regions in processing emotional significance.

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