Weight Reduction through Exercise and Meal Replacement Plan

An exercise plan consisting of a six-week introduction phase and supervised group sessions led to an average 13-kilogram weight reduction among 195 randomized patients. Responders achieving 5% weight loss in early intervention showed long-term benefits. At one year, the exercise group further reduced weight by 4 kilograms, while the group using loraglotide had a 7-kilogram reduction.