Inner Cosmos with David Eagleman cover image

Ep48 "Why do brains become depressed?"

Inner Cosmos with David Eagleman

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Understanding the Roots of Despair

Human brains exhibit a tendency to slip into despair due to evolutionary biology, suggesting a shared experience of depression among many animals, including pets like dogs and cats, elephants, and even zebrafish. This capacity for depression is believed to stem from ancient neural circuits designed for threat defense, indicating that the mechanisms for experiencing distress and withdrawing from positive experiences are deeply embedded and may serve a protective function.

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