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Ketamine: Benefits and Risks for Depression, PTSD & Neuroplasticity
Huberman Lab
Ketamine Dosage Regimens and Relief from Depression
Not all studies of using ketamine for depression have used the exact dosage regimen mentioned in the podcast./nDifferent studies have explored various dosage regimens./nKetamine provides immediate relief from depressive symptoms./nStacking ketamine treatments closely together can provide ongoing relief from depression./nKetamine likely acts through multiple mechanisms to provide relief from depression./nOne mechanism induces quick relief and is associated with a euphoric state./nAnother mechanism provides relief in the days and weeks after treatment./nA third mechanism induces long-lasting changes in the nervous system./nThese mechanisms create changes in neurochemistry and neural circuit wiring that alleviate depression./nUnderstanding ketamine's mechanisms can lead to insight about depression and neuroplasticity.
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