Recent studies indicate that higher levels of LDL cholesterol are correlated with increased odds of reaching the age of 100, challenging the prevailing belief that lower cholesterol is always better. It suggests that individuals with low LDL cholesterol at age 65 may have reduced chances of becoming centenarians. Additionally, lower blood glucose levels, lower liver enzymes, and higher albumin levels are associated with greater odds of longevity. Specifically, individuals with prediabetes often exhibit elevated liver enzymes, and maintaining these enzymes in the range of approximately 20-25 units per liter is beneficial. The findings encourage a reevaluation of current health guidelines for cholesterol and other metabolic markers in the context of aging and longevity.

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