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#112 ANA (Antinuclear Antibody) Test: 5 Pearls Segment

Core IM | Internal Medicine Podcast

NOTE

Antibodies often precede symptoms

Autoantibodies, specifically ANA, can be present in individuals for years before the onset of autoimmune diseases such as lupus. A study of military recruits revealed that a significant number exhibited positive ANAs well before being diagnosed, with some maintaining these markers as long as nine years without any symptoms. This insight emphasizes the importance of monitoring autoantibody presence in patients, even in the absence of noticeable autoimmune symptoms, as it could indicate a future diagnosis.

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