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#525: Cholesterol-Lowering Medication – Dr. Paddy Barrett

Sigma Nutrition Radio

NOTE

Optimizing Statin Therapy with Combination Approach

Using low dose statin therapy initially can often achieve a significant reduction in LDL levels, with a diminishing return as the dose increases. Higher doses of statin therapy may lead to increased side effects. Therefore, a combination approach with low dose statin therapy, along with other medications targeting different pathways, can be an effective strategy to reach target LDL levels. Combining low dose statin therapy with medications like ezetimibe and bempedoic acid can result in a substantial reduction in lipid burden, providing an alternative to high dose statin therapy.

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