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#314 ‒ Rethinking nutrition science: the evolving landscape of obesity treatment, GLP-1 agonists, protein, and the need for higher research standards | David Allison, Ph.D.

The Peter Attia Drive

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Genetics and Obesity: A Complex Interplay

The obesity epidemic is influenced by multiple interconnected factors, primarily food supply and availability. Additionally, there are intergenerational effects where genetic and epigenetic changes play a role. Genetic factors, particularly, influence obesity through mechanisms like assortative mating, differential fertility, and migration. Research indicates that individuals within certain BMI ranges tend to have more children, highlighting that the number of offspring produced varies with body weight. While it's recognized that obesity may come with fertility challenges, the overall reproductive output is shaped by these diverse genetic influences and societal behavior regarding family planning.

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