#316 - The Brain From the Inside-Out: A Dialogue with György Buzsáki
Converging Dialogues
Exploring the Complexities of Dopamine and Reinforcement in Brain Function
The shift from negative to positive responses in the brain involves a complex interaction with dopamine. Dopamine, considered a reinforcer, acts as a simple modulator that does not make decisions but plays a significant role in brain function. The number of dopamine neurons in the brain escalates with the brain's size, indicating a fundamental connection between brain size and the need for more dopamine neurons. The brain's organization in loops suggests that larger brains require access to various neural modulators like dopamine. Dopamine neurons in the VTA become more intricate due to connections with smart cortical areas, enhancing their functionality. This perspective highlights the interconnectedness of brain regions and the circular control system that governs brain function.
