Leaky brain occurs when the blood brain barrier becomes permeable, allowing particles and pathogens to pass through. Tight junctions can break down due to factors like poor diet, leading to leaky brain. The blood brain barrier is thin and consists of endothelial blood vessels and astroglial cells. Research shows a high correlation between gut and blood brain permeability. Zonulin, a protein released during infections like gluten sensitivity, opens up tight junctions in both the gut and the brain. Factors like low antioxidant levels, environmental pollutants, and inflammation can contribute to the breakdown of these barriers. When the blood brain barrier is permeable, glial cells in the brain can be exposed to pathogens and proteins, leading to an inflammatory cascade and symptoms like brain fog. Traumatic brain injuries can also break down the blood brain barrier. While the barriers have a protective function, a modern lifestyle with high oxidative stress and inflammation causes them to be consistently open, allowing harmful substances into the brain.

Get the Snipd
podcast app

Unlock the knowledge in podcasts with the podcast player of the future.
App store bannerPlay store banner

AI-powered
podcast player

Listen to all your favourite podcasts with AI-powered features

Discover
highlights

Listen to the best highlights from the podcasts you love and dive into the full episode

Save any
moment

Hear something you like? Tap your headphones to save it with AI-generated key takeaways

Share
& Export

Send highlights to Twitter, WhatsApp or export them to Notion, Readwise & more

AI-powered
podcast player

Listen to all your favourite podcasts with AI-powered features

Discover
highlights

Listen to the best highlights from the podcasts you love and dive into the full episode