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#317 ‒ Reforming medicine: uncovering blind spots, challenging the norm, and embracing innovation | Marty Makary, M.D., M.P.H.

The Peter Attia Drive

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Causality is King in Scientific Inquiry

In scientific research, it is crucial to recognize and question the potential confounding variables that may influence outcomes. The necessity of determining whether observed correlations truly indicate causality underlines the importance of rigorous evaluation of study designs. Significant observations from studies, such as a dose-dependent relationship between antibiotic use and health outcomes, should prompt further investigation of causal mechanisms rather than mere assumptions. The more evidence and repetition from large-scale studies, the stronger the signal of a potential causal relationship becomes. Ultimately, the pursuit of causality remains the cornerstone of scientific understanding, as without it, claims lack foundational validity.

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