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Ep 180 Acetaminophen Poisoning – Pitfalls in Assessment and Management

Emergency Medicine Cases

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The Pitfalls of Only Having an ALT Available to Detect Acetaminophen Overdose

Toxicologists use ALT and AST levels to monitor patients with an acetaminophen overdose. High bilirubin levels can indicate liver failure but never interfere with acetaminophen levels, while serial ALT levels are necessary to catch delayed hepatic toxicity. AST is preferred because it rises and falls faster, indicating faster recovery.

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