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Mayo Clinic Talks cover image

Menopause and Women's Health Edition | Topical and Non-Hormonal Therapies

Mayo Clinic Talks

NOTE

Exploring Non-Hormonal Therapies for Menopausal Symptoms

Non-hormonal therapies like medication requiring regular liver function testing can help manage menopausal symptoms such as hot flashes, abdominal pain, sleep disturbances, irritability, mood symptoms, and heart palpitations. Sleep disturbances often respond well to cognitive-based therapy, while heart palpitations may improve alongside other vasomotor symptoms being treated. Medications like oxybutynin, gabapentin, and SSRIs/SNRIs, though not FDA-approved, have shown efficacy in managing vasomotor symptoms for women who cannot take hormones, for example, due to cancer treatments, or those experiencing multiple symptoms.

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