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**Why psychedelics work in the brain. Serotonin 2a receptors. **
Psychedelic drugs like psilocybin, LSD, and DMT lead to a breakdown in brain networks while increasing communication between them. This results in a global increase in functional integrity. The action of these drugs is initiated by stimulating a specific serotonin receptor. MDMA, on the other hand, releases serotonin, making it unique among other compounds.