#521: How Does Coffee Impact Our Health?
Sigma Nutrition Radio
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Metabolism of Polyphenols and Health Benefits
Polyphenols are metabolized in the liver like xenobiotics, producing a large number of metabolites with biological activity. These metabolites act as signaling molecules in various tissues, rather than directly as antioxidants, leading to positive health benefits. The diversity of metabolites contributes to the different effects polyphenols have on bodily systems. The unique metabolism of polyphenols is likely responsible for their health benefits, despite concerns raised about their xenobiotic-like metabolism.
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