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#518: Nutritional Geometry, Philosophy of Science & A Case for Reductionism – Prof. David Raubenheimer & Jonathan Sholl, PhD

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Understanding Dietary Fats and Cholesterol through Reductionist Methods

Ansel Keys laid the foundation for understanding the impact of different types of dietary fats on blood cholesterol levels. Through reductionist methods, researchers have been able to distinguish between saturated, polyunsaturated, monounsaturated, and trans fats, and comprehend how each type affects blood cholesterol. By tracking specific biomarkers in the blood and conducting meticulous analysis, it has been established that saturated fat plays a crucial role in impacting blood cholesterol levels and subsequent cardiovascular disease outcomes. This in-depth understanding was achieved not by discarding reductionism but by embracing it at more appropriate levels to dissect the complexities of the system and clarify the significance of the diet-heart hypothesis.

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