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69. What’s to blame for Insulin Resistance, Carbs or PUFAs? A very friendly debate with Ben Bikman, PhD

Paul Saladino MD podcast

NOTE

Switching Fat Cell Growth for Insulin Sensitivity

Switching fat cell growth from hypertrophy to hyperplasia through drug action like thiazolidine diones (TZDs) can lead to more fat cells of modest size, making individuals insulin sensitive. This process may lead to rapid weight gain due to increased fat cells, which can be largely attributed to the drug's mechanism and paradoxically making individuals fatter than before.

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