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The Peter Attia Drive cover image

#317 ‒ Reforming medicine: uncovering blind spots, challenging the norm, and embracing innovation | Marty Makary, M.D., M.P.H.

The Peter Attia Drive

NOTE

Causality Over Correlation

Adopting a scientific mindset requires scrutiny of potential confounding variables when examining a study's results. Observations, even if repeated in large cohorts, do not imply causation without further investigation. The strength of evidence is strengthened by dose-dependent relationships, indicating that effects may increase with greater exposure. Establishing causality is essential in science, serving as the foundation for understanding phenomena. Causation must be supported by statistical analyses, as outlined by criteria from Austin Bradford Hill, which assess the strength and likelihood of an association being causal.

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