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#148 Iron Deficiency Treatment: 5 Pearls Segment

Core IM | Internal Medicine Podcast

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Choosing IV Iron over PO Iron

Hepcidin degrades feroportin, leading to iron dropping in the gut and being sequestered in macrophages, preventing absorption. Conditions like chronic inflammatory disorders, heart failure, and IBD may benefit from IV iron due to impaired absorption or potential harm from oral iron, particularly in exacerbating IBD by harming the microbiome and disrupting bacterial diversity.

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