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286 | Blaise Agüera y Arcas on the Emergence of Replication and Computation

Sean Carroll's Mindscape: Science, Society, Philosophy, Culture, Arts, and Ideas

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From Autocatalysis to Heritability

A significant transformation occurs during abiogenesis when simple autocatalytic sets evolve into entities with genomes. This change introduces a structured list of instructions for self-replication, leading to heritability. This concept links to foundational biological ideas explored by John von Neumann, who, alongside Stan Ulam, developed cellular automata and a cell-free production system. Von Neumann's theoretical work laid the groundwork for understanding complex biological processes, despite being less recognized within traditional biology.

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