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Ketamine: Benefits and Risks for Depression, PTSD & Neuroplasticity
Huberman Lab
Understanding Depression in Preclinical Animal Models
The model of learned helplessness, which involves putting animals into water to measure their resilience, is a valuable tool for studying depression in preclinical animal models./nThe use of drugs to prolong the duration over which the animal attempts to save its own life in the learned helplessness model can provide insights into potential treatments for depression./nThe symptom of a negative outlook on the future is a hallmark of depression, while consistently waking up early in the morning is one of its prominent symptoms./nHowever, waking up early and inability to fall back asleep does not necessarily indicate depression.
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