Psychedelics have shown to have a positive impact on depression through inducing ego death experiences. Research suggests that the level of ego dissolution during a psychedelic trip determines the extent to which depression improves. Individuals who experience ego death during psychedelic therapy exhibit significant improvement in depression, while those who do not undergo ego dissolution see no change in their depressive state. The therapeutic value of psychedelics lies in activating ego death, allowing individuals to feel connected to others and fostering a sense of compassion, ultimately leading to positive outcomes in treating depression.